We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
ARAB HEALTH - INFORMA

Download Mobile App




World’s Most Sensitive Flexible Strain Sensor Enables Real-Time Stroke Monitoring

By HospiMedica International staff writers
Posted on 23 Dec 2024
Print article
Image: Schematic illustration of biomechanical signal monitoring on the vascular surface of a canine brain model (Photo courtesy of Science Advances, doi/10.1126/sciadv.ads9258)
Image: Schematic illustration of biomechanical signal monitoring on the vascular surface of a canine brain model (Photo courtesy of Science Advances, doi/10.1126/sciadv.ads9258)

Flexible and stretchable strain sensors are designed to detect biomechanical signals or measure deformation in objects by monitoring changes in the electrical resistance of conductive materials. However, current sensors struggle with low sensitivity and performance degradation when measuring very small strains, specifically those below 10−3. This limitation presents significant challenges, particularly in the early diagnosis of diseases linked to mechanical physiological signals, as well as in assessing structural reliability and conducting preemptive safety evaluations. For example, cerebrovascular conditions like brain hemorrhages or ischemia produce infinitesimal strains smaller than 10−3 before they become critical. Similarly, structural materials typically experience strains of 10−5 to 10−3 on their surfaces prior to catastrophic failure, which can result in substantial loss of life. Now, a groundbreaking study has introduced a hypersensitive, flexible, and stretchable sensor by combining microcracks with meta-structures in a novel way. This technology enables real-time stroke diagnosis through continuous blood flow monitoring, marking a significant advancement in precision biomedical engineering.

Researchers from Seoul National University College of Engineering (SNU, Seoul, Korea), in collaboration with other experts, have developed a strain sensor that outperforms existing sensors in sensitivity. The team incorporated a meta-structure with a negative Poisson's ratio, which enhanced the sensor's sensitivity by up to 100 times compared to previous versions. This new sensor can detect strains as small as 10−5, which corresponds to a length change comparable to a single atom on the surface of a human hair. The breakthrough in sensitivity was achieved by amplifying electrical resistance changes through the controlled widening of nanoscale microcracks. This approach enabled the sensor to monitor extremely small deformations, such as those occurring during microbial growth, like the real-time detection of strain caused by the growth of mold hyphae on bread, which generates strain as tiny as 10−5.

The sensor also shows immense promise for biological applications. The research team successfully attached the sensor to the surface of cerebral blood vessels inside the skull, enabling real-time monitoring of blood pressure and blood flow changes. This innovation highlights the sensor's potential for the early detection of cerebrovascular diseases, including cerebral hemorrhages and ischemia, as well as cardiovascular disorders, providing highly accurate medical data. Additionally, the sensor is made from biodegradable materials, which allows it to decompose naturally without leaving long-term residue in the body, ensuring patient safety and eliminating the need for further surgeries or side effects. The findings of this study, published in Science Advances, have drawn significant attention due to the combination of cutting-edge technology and its practical, real-world applications.

"This study is not merely about improving sensor performance, but about presenting a groundbreaking approach that overcomes the fundamental limitations of the previous technologies," stated the research team. "We anticipate wide-ranging applications not only in bioengineering and medical devices but also in fields such as robotics, disaster response, and environmental monitoring."

Gold Member
STI Test
Vivalytic Sexually Transmitted Infection (STI) Array
Gold Member
POC Blood Gas Analyzer
Stat Profile Prime Plus
New
MRI System
Ingenia Prodiva 1.5T CS
New
Hand Fixation Device
Hand Fixation Device

Print article

Channels

Surgical Techniques

view channel
Image: Alizarin red staining, highlighting sites of mineralization, in a PLAG5 20% scaffold (Photo courtesy of Biomaterials Advances, DOI: 10.1016/j.bioadv.2024.213985)

Novel 3D Printed Scaffolds Ensure Better Healing and Regeneration of Bone Tissue

Critical bone defects caused by trauma, tumor removal, or congenital conditions pose significant treatment challenges due to the high likelihood of graft failure, often resulting from poor blood supply.... Read more

Patient Care

view channel
Image: The portable biosensor platform uses printed electrochemical sensors for the rapid, selective detection of Staphylococcus aureus (Photo courtesy of AIMPLAS)

Portable Biosensor Platform to Reduce Hospital-Acquired Infections

Approximately 4 million patients in the European Union acquire healthcare-associated infections (HAIs) or nosocomial infections each year, with around 37,000 deaths directly resulting from these infections,... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The acoustic pipette uses sound waves to test for biomarkers in blood (Photo courtesy of Patrick Campbell/CU Boulder)

Handheld, Sound-Based Diagnostic System Delivers Bedside Blood Test Results in An Hour

Patients who go to a doctor for a blood test often have to contend with a needle and syringe, followed by a long wait—sometimes hours or even days—for lab results. Scientists have been working hard to... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.