The LOCalizer Wireless Surgical Guidance System is a cutting-edge solution for precise localization of breast lesions during surgeries. It utilizes radiofrequency identification (RFID) technology, allowing for accurate and efficient targeting without the need for traditional wire localization. The system includes an RFID tag that can be implanted days before surgery, a handheld reader to detect the tag, and a surgical probe to guide excision. This approach enhances patient comfort, streamlines workflow, and improves surgical outcomes by providing real-time feedback during procedures.