Electrospinning Technology Treats Burns from Afar

The Nanomedic Technologies (Lod, Israel) SpinCare device is a portable wound care system that creates an on-the-spot protective nano-fibrous layer that facilitates tissue repair and healing of second-degree burns, surgical wounds, large lacerations and partial deep wounds, all without any contact from the caregiver. The protective layer is applied about 20 cm away from the wound, and is applied only once. It then remains on the wound throughout the healing process, allowing growth of new skin underneath it.

The electrospun nanofibers, which can be made from most natural or synthetic polymers, create a nanofibrous mat, which mimics the natural extra cellular matrix (ECM), encouraging quick and efficient tissue integration and minimizing medical complications. The technology can address various stages of the healing process by allowing the combination of additives such as antibacterial, antibiotics, collagen, cannabinoids, silicon, and hydrogels into the electrospun nanofibers, providing an excellent scaffold for growth and an active or passive protective layer.

“There is also a reduced risk for infection because the wound is never touched, and you don’t need to replace it. Typically, the major pain that patients complain about is the traumatic changing of dressings. Here you skip this step, and this is crucial for the patient and for the caregiver,” said Chen Barak, MD, CEO of Nanomedic Technologies. “After our application, you can go back to regular day-to-day life, including early showers and free movement.”

Electrospinning technology allows tight control of matrix characteristics, including shape (flat, tubular, or contoured); size (length, width, and thickness); fiber diameter; pore size; and porosity (0%-95%). Both natural materials such as collagen, chitosan, or DNA can be used, as well as stable or biodegradable polymers, such as polylactic-co-glycolic acid (PLGA), poly-L-Lysine (PLL), polyvinyl alcohol (PVA), and other. Many additives can be incorporated as well, such as drugs and nanoparticles, either inside, on the surface, or between the fibers. The final product can be formed as a single or multilayer mesh, a film, gels, or coatings, and either transparent or opaque.

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